Functional integration of a metabolic network model and expression data without arbitrary thresholding
نویسندگان
چکیده
منابع مشابه
Functional integration of a metabolic network model and expression data without arbitrary thresholding
MOTIVATION Flux balance analysis (FBA) has been used extensively to analyze genome-scale, constraint-based models of metabolism in a variety of organisms. The predictive accuracy of such models has recently been improved through the integration of high-throughput expression profiles of metabolic genes and proteins. However, extensions of FBA often require that such data be discretized a priori ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2010
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btq702